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小奥今日向大家介绍Dupilumab 度普利尤单抗(CAS号:1190264-60-8)!
Dupilumab 度普利尤单抗
Dupilumab(度普利尤单抗) 是一种潜在首创的(first-in-class),针对 IL-4 受体α (IL-4Rα) 的完全人源化的单克隆抗体,可抑制 IL-4 和 IL-13 信号转导,能用于特应性皮炎和哮喘的相关研究。
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化学性质
CAS号:1190264-60-8
储存条件:Please store the product under the recommended conditions in the Certificate of Analysis.
运输方式:冰袋运输,根据产品的不同,可能会有相应调整。
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参考文献
[1] Evan S Dellon, et al. N Engl J Med. Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis
[2] Shanthi Narla, et al. J Am Acad Dermatol. Management of inadequate response and adverse effects to dupilumab in atopic dermatitis
[3] F J Muñoz-Bellido, et al. J Investig Allergol Clin Immunol. Dupilumab: A Review of Present Indications and Off-Label Uses
[4] Mario Castro, et al. N Engl J Med. Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma
[5] Marlene Seegräber, et al. Expert Rev Clin Pharmacol. Dupilumab for treatment of atopic dermatitis
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